e381
Also listed as: E381
Synthetic preservative or chemical colorant. Linked in clinical pediatric trials to hyperactivity. Can react under acidic conditions to form carcinogens (like benzene). May cause severe allergic histamine release.
- MicroplasticsNot flagged
- SugarsNot flagged
- Seed OilsNot flagged
- Immune System
- Brain / Neurological
- Liver
- FDASubject to strict maximum parts-per-million limits
- EFSARequires warning labels for children's developmental impact
PubMed References
Food additives and hyperactive behavior in 3-year-old and 8/9-year-old children: a double-blind study(2022)
PubMed (PMID 17825405)→Last reviewed: May 2026
FAQ
Is e381 bad for you?
Synthetic preservative or chemical colorant. Linked in clinical pediatric trials to hyperactivity. Can react under acidic conditions to form carcinogens (like benzene). May cause severe allergic histamine release.
What does e381 do to your body?
e381 primarily affects: Immune System, Brain / Neurological, Liver.
How often is it safe to consume e381?
Daily: Avoid — suspected genotoxic and behavioral risks. Weekly: Avoid in children's diet. Monthly: Safe for occasional consumption.
What products contain e381?
e381 is commonly found in food products. Use the Zeral app to scan any product and instantly see if it contains e381.
Related Ingredients
Other Food ingredients you should know about
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Medical Disclaimer: The information on this page is compiled from peer-reviewed scientific studies and regulatory reports. It is intended for general awareness and educational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.