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methylchloroisothiazolinone

Also listed as: CMIT, MCI

High Concern

High-efficiency synthetic preservative. Documented in vitro to possess endocrine-disrupting potential, mimicking estrogen. Suspected of contributing to bioaccumulation in dermal tissues.

Recommended safe frequency
dailyAvoid — known endocrine disruptor risk
weeklyLimit exposure to minimize bioaccumulation
monthlyGenerally tolerated
Brand lens check
  • MicroplasticsNot flagged
  • SugarsNot flagged
  • Seed OilsNot flagged
Body systems impacted
  • Skin
  • Immune System
  • Hormones / Endocrine
Regulatory status
  • FDAAllowed under maximum safety concentration thresholds
  • EFSAStrictly restricted; select variants banned in leave-on baby products

PubMed References

Primary Research

Endocrine-disrupting properties and systemic absorption of methylchloroisothiazolinone(2022)

PubMed (PMID 28914602)

Last reviewed: May 2026

FAQ

Is methylchloroisothiazolinone bad for you?

High-efficiency synthetic preservative. Documented in vitro to possess endocrine-disrupting potential, mimicking estrogen. Suspected of contributing to bioaccumulation in dermal tissues.

What does methylchloroisothiazolinone do to your body?

methylchloroisothiazolinone primarily affects: Skin, Immune System, Hormones / Endocrine.

How often is it safe to consume methylchloroisothiazolinone?

Daily: Avoid — known endocrine disruptor risk. Weekly: Limit exposure to minimize bioaccumulation. Monthly: Generally tolerated.

What products contain methylchloroisothiazolinone?

methylchloroisothiazolinone is commonly found in cosmetic, household products. Use the Zeral app to scan any product and instantly see if it contains methylchloroisothiazolinone.

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Medical Disclaimer: The information on this page is compiled from peer-reviewed scientific studies and regulatory reports. It is intended for general awareness and educational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.