poloxamer 188
Synthetic surfactant or stabilizer. Chronic topical application is clinically documented to disrupt the epidermal lipid barrier, increase skin permeability, and trigger contact dermatitis.
- MicroplasticsNot flagged
- SugarsNot flagged
- Seed OilsNot flagged
- Skin
- Immune System
- FDAAllowed in cosmetic formulations; concentration limits apply
- EFSAApproved up to restricted limits; flagged for dermal irritation
PubMed References
Contact allergy and skin barrier disruption caused by poloxamer 188(2022)
PubMed (PMID 30284712)→Last reviewed: May 2026
FAQ
Is poloxamer 188 bad for you?
Synthetic surfactant or stabilizer. Chronic topical application is clinically documented to disrupt the epidermal lipid barrier, increase skin permeability, and trigger contact dermatitis.
What does poloxamer 188 do to your body?
poloxamer 188 primarily affects: Skin, Immune System.
How often is it safe to consume poloxamer 188?
Daily: Avoid on broken, sensitive, or eczema-prone skin. Weekly: Safe in rinse-off products only. Monthly: Generally tolerated.
What products contain poloxamer 188?
poloxamer 188 is commonly found in cosmetic products. Use the Zeral app to scan any product and instantly see if it contains poloxamer 188.
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Medical Disclaimer: The information on this page is compiled from peer-reviewed scientific studies and regulatory reports. It is intended for general awareness and educational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.