poloxamer 407
Synthetic surfactant or stabilizer. Chronic topical application is clinically documented to disrupt the epidermal lipid barrier, increase skin permeability, and trigger contact dermatitis.
- MicroplasticsNot flagged
- SugarsNot flagged
- Seed OilsNot flagged
- Skin
- Immune System
- FDAAllowed in cosmetic formulations; concentration limits apply
- EFSAApproved up to restricted limits; flagged for dermal irritation
PubMed References
Contact allergy and skin barrier disruption caused by poloxamer 407(2022)
PubMed (PMID 30284712)→Last reviewed: May 2026
FAQ
Is poloxamer 407 bad for you?
Synthetic surfactant or stabilizer. Chronic topical application is clinically documented to disrupt the epidermal lipid barrier, increase skin permeability, and trigger contact dermatitis.
What does poloxamer 407 do to your body?
poloxamer 407 primarily affects: Skin, Immune System.
How often is it safe to consume poloxamer 407?
Daily: Avoid on broken, sensitive, or eczema-prone skin. Weekly: Safe in rinse-off products only. Monthly: Generally tolerated.
What products contain poloxamer 407?
poloxamer 407 is commonly found in cosmetic products. Use the Zeral app to scan any product and instantly see if it contains poloxamer 407.
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Medical Disclaimer: The information on this page is compiled from peer-reviewed scientific studies and regulatory reports. It is intended for general awareness and educational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.