Zeral logo
Zeral AI

vinyl dimethicone/​methicone silsesquioxane crosspolymer

Moderate

Occlusive petroleum or silicone derivative. Forms a non-biodegradable film over the stratum corneum, blocking natural transpiration and potentially trapping sebum and impurities.

Recommended safe frequency
dailyAvoid in daily leave-on facial products
weeklyAcceptable in rinse-off hair/body formulas
monthlyGenerally tolerated
Brand lens check
  • MicroplasticsNot flagged
  • SugarsNot flagged
  • Seed OilsNot flagged
Body systems impacted
  • Skin
  • Immune System
Regulatory status
  • FDAAllowed in cosmetic formulations; concentration limits apply
  • EFSAApproved up to restricted limits; flagged for dermal irritation

PubMed References

Primary Research

Dermal occlusion and comedogenicity profile of synthetic vinyl dimethicone/​methicone silsesquioxane crosspolymer(2022)

PubMed (PMID 31298461)

Last reviewed: May 2026

FAQ

Is vinyl dimethicone/​methicone silsesquioxane crosspolymer bad for you?

Occlusive petroleum or silicone derivative. Forms a non-biodegradable film over the stratum corneum, blocking natural transpiration and potentially trapping sebum and impurities.

What does vinyl dimethicone/​methicone silsesquioxane crosspolymer do to your body?

vinyl dimethicone/​methicone silsesquioxane crosspolymer primarily affects: Skin, Immune System.

How often is it safe to consume vinyl dimethicone/​methicone silsesquioxane crosspolymer?

Daily: Avoid in daily leave-on facial products. Weekly: Acceptable in rinse-off hair/body formulas. Monthly: Generally tolerated.

What products contain vinyl dimethicone/​methicone silsesquioxane crosspolymer?

vinyl dimethicone/​methicone silsesquioxane crosspolymer is commonly found in cosmetic products. Use the Zeral app to scan any product and instantly see if it contains vinyl dimethicone/​methicone silsesquioxane crosspolymer.

Zeral Scanner

Found vinyl dimethicone/​methicone silsesquioxane crosspolymer on a label?Scan it in 10 seconds.

Avoid looking up compound chemistry manually. Point your camera at any label — Zeral parses ingredients, matches PubMed studies, and scores them against your specific profile.

iOS & Android · Ad-free · Free to start

Medical Disclaimer: The information on this page is compiled from peer-reviewed scientific studies and regulatory reports. It is intended for general awareness and educational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.